A new study published in the American Society for Microbiology journal Microbiology Spectrum demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant strains. The new compound provides a promising chemical scaffold to develop new potent anti-tuberculosis drugs.
Researchers have identified a modified compound from the bloodroot plant, native to North America, that exhibits potent activity against multidrug-resistant tuberculosis (TB) bacteria in laboratory settings.
This compound not only suppresses dormant TB bacteria but also avoids harming the gut microbiome, a common issue with many antibiotics.
The discovery holds promise for developing new treatments for TB, a disease that remains a leading cause of death worldwide, particularly in its drug-resistant forms.
Source. ScienceDaily. "Study identifies potential novel drug to treat tuberculosis" "https://www.sciencedaily.com/releases/2024/10/241003123257.htm?." October 3, 2024.
Edited by Ansh Pincha
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